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EP 299: How to Lower Dementia Risk: 12 Science-Backed Strategies w/ Dr. Yogesh Shah

Entrepreneurs United · 2026-05-25 · 49 min

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Episode notes

What if you could detect Alzheimer's years before any symptoms appeared and stop it? Dr. Yogesh Shah is a Board-Certified Geriatrician and Mayo Clinic-trained memory specialist who has spent 25 years focused entirely on the early detection and prevention of dementia. In this episode, he makes a case that every entrepreneur in their 40s and 50s needs to hear: the window to protect your brain is now. Not at 70. Not after a diagnosis. America spends 20% of its GDP on healthcare, and nearly all of it goes to disease management. Dr. Shah explains why that approach is failing, what Mild Cognitive Impairment is and why it matters, and how a new FDA-approved blood test can identify Alzheimer's pathology years before any symptoms appear. He walks through the 14 lifestyle factors identified in the Lancet study that can reduce dementia risk by up to 45%, and explains how monoclonal antibody infusions are now removing amyloid plaque from the brains of patients caught early enough.

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