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LLMs

A guide to the best B2B podcast coverage of LLMs - the shows and 44 episodes that go deepest, ranked by substance, not downloads.

Large language models are reshaping how B2B companies operate - from security implications explored by Smartsheet's CTO Cynthia Tee, to stakeholder management approaches at Capgemini, to accessibility standards championed by Moleworks' Rachael Mole. Beyond internal adoption challenges like those Descript's CEO tackled, LLMs are fundamentally altering B2B buying behavior and partnership strategies, with PartnerStack examining how AI affects distribution and trust, while simultaneously creating new vulnerabilities and content ranking dynamics that companies like those featured in recent episodes are actively navigating.

Best shows on LLMs

Best episodes on LLMs

  1. Evolving Executive Leadership with Agentic AI (Elise Neel)

    What’s the BUZZ? - AI in Business · 2026-04-18

    81 / 100

    …And so instead, as we think about collaboration, these machines and LLMs by their very nature, their, inherent nature is to take this swarm complex to think about connections that.…

  2. PayPal Ads’ Big Retail Media Bet: Why Shoppable Ads Could Finally Work (And The Future of Commerce in an AI World)

    Retail Media Breakfast Club · 2026-06-23

    80 / 100

    …What I mean by that is that a lot of the consumer behaviors now [00:10:00] start on LLMs.…

  3. How Klaviyo is Redefining B2C CRM, Services, and AI with Grant Deken, Head of Product of Klaviyo Services

    Lessons In Product Management · 2025-08-19

    80 / 100

    …So I want to give you the floor and um, just kind of share like how is Genai and this whole machine learning revolution LLMs impacting Klaviyo as a business?…

  4. AI Security: Patricia Titus on Shadow AI, Non-Human Identities, and AI Defense

    AI Security, Cyber Risk, and Cloud Strategy on ClearTech Loop · 2026-05-27

    79 / 100

    …The LLMs, I feel like people are being a little more purposeful about those, like the agents have, like, gotten loose, like gnomes in our systems, and they are just.…

  5. The Truth About The Recent Vulnerability Spike w/ Aaron Mitchell | Episode 198

    The Software Leaders Uncensored Podcast · 2026-06-09

    75 / 100

    …Now with Claude and, and Codex and all of these LLMs pounding these open source libraries for, to look for vulnerabilities, that number looks like it could as much as double.…

  6. The Year In AI: What We Got Right and What Went Wrong in 2025

    Signal to Noise · 2026-01-06

    75 / 100

    …Right? Um, just like how LLMs were, by the way, two years ago when ChatGPT first came out, it was all about LLMs and AI, but we didn't actually see that being implemented in real life in a meaningful way.…

  7. #63 Throxy: The outbound company that ignored LinkedIn completely | Arnau Ayerbe

    Venturing with Vishesh · 2026-05-13

    71 / 100

    …Very early from the start, you could see hints that LLMs were simply this magical thing that were going to transform the way the world looked.…

  8. From Hostile to Rewired: How Descript's CEO Drives AI Adoption | Laura Burkhauser

    LaunchPod · 2026-06-16

    69 / 100

    …And so when LLMs came out, first of all, we kind of got multimodal editing for free because if you think about video as a document, what are LLMs incredibly good at doing?…

  9. The Machine Ate the Storefront, PayPal Mapped the Collapse

    Future Commerce · 2026-06-10

    69 / 100

    …Instead what they're doing is to actually start the search on LLMs.…

  10. The Truth About AI Content, SEO, and What Actually Ranks in 2026 with Kyle Roof

    Revenue Optimization with StatsDrone · 2026-04-30

    67 / 100

    …Um, but the biggest thing we've actually been running a year long case study, um, we're a little bit over a year now and looking um, at kind of the base level of terms that we get out of the LLMs, like without prompting, what, what is the content that we're getting?…

  11. Accessible AI Is Better Business, with Rachael Mole - Moleworks [084]

    The Business of AI · 2026-06-18

    66 / 100

    …So in this respect we're talking about generative AIs and LLMs.…

  12. AI, Security, and the Courage to Reinvent with Smartsheet CTO Cynthia Tee

    Shift AI Podcast · 2026-06-26

    66 / 100

    …If we didn't have generative AI and LLMs, it would be, uh, just very challenging to make an easier interface.…

  13. #53 Ask Me Anything

    Playing With Unicorns · 2026-03-23

    64 / 100

    …In the near term, um, uh, it'll be an open cloud type agent embedded or provided by the core, um, uh, by the core marketplaces, um, sorry, the core AI LLMs like Claude or OpenAI that will offer an open cloud equivalent without any of the security concerns and risks that you're, that you're seeing today.…

  14. Episode 34: Building a Better Customer Feedback Engine with Brannon Santos (Founder & CEO at ChatGems)

    The Founder's Formula Podcast · 2023-09-12

    54 / 100

    …When we saw LLMs come out in popularity and usability six months ago, one of the first thoughts that I had was can I leverage the LLM to extract new insights from humans rather than asking it to go extract insights from a corpus of data…

  15. Faith, The Machine Average & Staying Human in the Age of AI w/ Abhijith Ravinutala

    It's Not the End of the World: Everyday Use Cases for AI · 2026-02-27

    49 / 100
  16. How is AI changing B2B buying behavior and making partnerships more important for distribution and trust? | Bryn Jones, Co-Founder, PartnerStack

    Straight To Voicemail · 2026-06-16

    47 / 100

    …But now buyers are showing up out after spending time inside of LLMs, um, community threads and conversations in areas that they already trust.…

  17. Pull Up a Chair: A Conversation with Lena Redko

    Analytics Friday · 2026-05-14

    46 / 100

    …It's uh, how you differentiate because LLMs are so intelligent if uh, they are not um, um elevated in some way by the human side and to give different aspects and blind spots and strategy.…

  18. How Living Corporate Supported Capgemini's Stakeholder Management Strategy with AI ! Ft. Janet Pope

    Living Corporate · 2026-06-23

    45 / 100

    …We have some things that we've done that are proprietary and how we, how we leverage certain LLMs.…

  19. Cross-Functionally Leveraging AI for Good with Claudine Ryan, President of TalkingPoints

    The Data Cloud Podcast · 2024-06-25

  20. August 2025 AI Pulse

    Disambiguation · 2025-08-21

  21. When AI Agents Cross the Boundary: Securing the AI Factory

    AI Proving Ground Podcast · 2026-07-29

  22. Preetam Joshi Breaks Down ML, LLMs, AI Agents, and Governance Challenges

    Security & GRC Decoded · 2025-07-10

  23. Structured Thinking for Unstructured Data: A Conversation with Founder Kirk Marple

    Prodity: Product by Design · 2025-04-10

    …And um, then with LLMs started to realize this fits really well.…

  24. Episode 16: How Human-Centered AI Actually Gets Built

    High Signal · 2025-05-13

  25. Episode 15: Why Good Metrics Still Lead to Bad Decisions - and How to Fix It

    High Signal · 2025-04-24

  26. Episode 14: Why Most Companies Aren’t Actually AI Ready (and What to Do About It)

    High Signal · 2025-04-10

  27. Episode 13: The End of Programming As We Know It

    High Signal · 2025-03-27

  28. Episode 7: What Lies Beyond Machine Learning and AI: Decision Systems and the Future of Data Teams

    High Signal · 2024-12-19

  29. Episode 6: What Happens to Data Science in the Age of AI?

    High Signal · 2024-12-04

  30. Episode 18: High-Stakes AI Systems and the Cost of Getting It Wrong

    High Signal · 2025-06-19

  31. The Death of Data Gatekeeping: AI Makes Everyone An Analyst | Hex Cofounder

    AI + a16z · 2025-12-05

  32. What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

    AI + a16z · 2026-03-17

  33. Inferact: Building the Infrastructure That Runs Modern AI

    AI + a16z · 2026-01-22

  34. From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu

    AI + a16z · 2025-11-25

  35. How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era

    AI + a16z · 2025-11-18

  36. Performance and Passion: Fal's Approach to AI Inference

    AI + a16z · 2025-08-01

  37. How to Vibe Code Securely

    AI + a16z · 2025-07-25

  38. AI's Unsung Hero: Data Labeling and Expert Evals

    AI + a16z · 2025-06-27

  39. AI, Data Engineering, and the Modern Data Stack

    AI + a16z · 2025-06-20

  40. Enabling Agents and Battling Bots on an AI-Centric Web

    AI + a16z · 2025-06-13

  41. Giving New Life to Unstructured Data with LLMs and Agents

    AI + a16z · 2025-06-06

  42. Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

    AI + a16z · 2025-05-30

  43. Building AI Systems You Can Trust

    AI + a16z · 2025-05-23

  44. Who's Coding Now? AI and the Future of Software Development

    AI + a16z · 2025-05-16