The B2B Podcast Index
Index
All categories
MarketingSalesSaaSFinanceHROpsLeadershipCustomer SuccessAI & DataProductStartups & FoundersRevOpsEngineering & DevTools
MethodologySubmit
Best of:MarketingSalesSaaSFinanceHROpsLeadershipCustomer SuccessAI & DataProductStartups & FoundersRevOpsEngineering & DevTools
An independent project byFame
SearchBest episodesGuestsInsightsMethodologySubmit a podcast
Index/AI & Data/AI + a16z
AI + a16z artwork

How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era

AI + a16z · 2025-11-18 · 57 min

0:00--:--

Topics in this episode

LLMsdspy

Episode notes

The Stanford PhD who built DSPy thought he was just creating better prompts - until he realized he'd accidentally invented a new paradigm that makes LLMs actually programmable. While everyone obsesses over whether LLMs will get us to AGI, Omar Khattab is solving a more urgent problem: the gap between what you want AI to do and your ability to tell it, the absence of a real programming language for intent. He argues the entire field has been approaching this backwards, treating natural language prompts as the interface when we actually need something between imperative code and pure English, and the implications could determine whether AI systems remain unpredictable black boxes or become the reliable infrastructure layer everyone's betting on. Follow Omar Khattab on X: Follow Martin Casado on X: Check out everything a16z is doing with artificial intelligence here , including articles, projects, and more podcasts. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Related episodes across the Index

Other episodes covering the same guests and topics, from across The B2B Podcast Index.

  • Evolving Executive Leadership with Agentic AI (Elise Neel)What’s the BUZZ? - AI in Business · on LLMs81 / 100
  • PayPal Ads’ Big Retail Media Bet: Why Shoppable Ads Could Finally Work (And The Future of Commerce in an AI World)Retail Media Breakfast Club · on LLMs80 / 100
  • How Klaviyo is Redefining B2C CRM, Services, and AI with Grant Deken, Head of Product of Klaviyo ServicesLessons In Product Management · on LLMs80 / 100
  • AI Security: Patricia Titus on Shadow AI, Non-Human Identities, and AI DefenseAI Security, Cyber Risk, and Cloud Strategy on ClearTech Loop · on LLMs79 / 100
  • The Truth About The Recent Vulnerability Spike w/ Aaron Mitchell | Episode 198The Software Leaders Uncensored Podcast · on LLMs75 / 100
  • The Year In AI: What We Got Right and What Went Wrong in 2025Signal to Noise · on LLMs75 / 100

More from AI + a16z

All episodes →
  • How AI Is Rewriting the Rules of Cybersecurity | Truffle Security & Socket95 / 100
  • Building Self-Accelerating AI with Mirendil65 / 100
  • Inside vLLM: The Engine Powering Open-Source AI
  • Ideogram’s Open-Weights Image Model and the Future of AI Design
  • Building Search for AI Agents with Exa CEO Will Bryk
Explore the best B2B AI & Data podcasts →
All AI + a16z episodes →