From Vector Databases to Knowledge Engines: The Next Layer of AI

Episode notes

Peter Levine speaks with Ash Ashutosh, CEO of Pinecone, about the launch of Nexus and the shift from vector databases to knowledge engines. As agents become the primary users of software, they discuss why traditional retrieval systems break down and how AI systems need to evolve to support machine-to-machine interactions. The conversation explores how agents currently spend most of their time retrieving and reasoning over data, why that approach is inefficient, and how moving reasoning closer to the data can dramatically improve performance, accuracy, and cost. Ash also explains how Pinecone is rethinking the stack for agentic applications, introducing new abstractions, query languages, and developer workflows. Resources: Follow Ash Ashutosh on X: Follow Peter Levine on LinkedIn: Check out everything a16z is doing with artificial intelligence here , including articles, projects, and more podcasts. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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