Institutional Capital and the Next Phase of On-Chain Finance with Andy Kangpan of Metalayer

Episode notes

Andy Kangpan is a Partner at Metalayer, a crypto-native investment firm focused on backing companies building institutional-grade financial infrastructure on blockchain rails. Founded by former Two Sigma investors and operators, Metalayer plays at the intersection of venture capital, on-chain markets, and next-generation asset management. Andy brings over a decade of experience in venture capital, with a background spanning early-stage technology investing and seven years at Two Sigma, where he led the firm's crypto venture efforts. During his tenure, he worked across private investments and liquid strategies, developing a deep understanding of how blockchain technology can be applied to reinvent core financial plumbing. At Metalayer, Andy focuses on seed and early-stage investments in companies building for the institutional phase of crypto - particularly where on-chain infrastructure intersects with regulated financial services. His work emphasizes disciplined portfolio construction, long-term value creation, and expanding the venture playbook to include new, on-chain-native investment strategies. Please enjoy the following insights from Andy Kangpan of Metalayer.

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