Life Science Success · 2026-01-29 · 57 min
Send us Fan Mail Jesse Mendelsohn and Michael Grosberg from Model N discuss why U.S. pricing complexity is spreading globally, the collapse of the PBM rebate model, what's really driving the pharmaceutical manufacturing boom, and why direct-to-consumer discount programs won't solve America's drug access problem. 00:00 Introduction to Life Science Success Podcast 00:34 Pressing Issues in Pharmaceutical Manufacturing 00:51 Introducing the Experts from Model N 03:08 Understanding International Reference Pricing 04:14 Impact of US Pricing on Global Drug Launches 09:26 Challenges with Pharmacy Benefit Managers 16:29 Domestic Manufacturing Boom in Pharmaceuticals 23:08 AI in Drug Discovery and Personalized Medicine 29:03 Access and Policy Discussion 30:01 Direct to Consumer Pricing 31:32 TrumpRx Overview 33:11 Compliance Challenges 38:30 Pharmaceutical Revenue Management 41:38 AI in Life Sciences 48:35 Future of Life Sciences 50:45 Concerns and Challenges 53:52 Excitement in Current Work 55:54 Conclusion and Final Thoughts
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