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Using AI at Work

104: Using AI Coworkers to Build Smarter Business Operations with Karl Simon

Using AI at Work · 2026-05-18 · 50 min

Episode notes

Send us Fan Mail Most companies are using AI, but very few are redesigning work around it. In this episode Chris sits down with Karl Simon, co-founder and CTO of Subatomic, an AI workflow orchestration company, to explore why task based AI adoption is limiting business impact. They discuss the shift from isolated AI use cases toward unified workflows powered by clean data, AI coworkers, and cross functional orchestration. The conversation also explores how organizations may flatten hierarchies as AI takes over information movement and decision support responsibilities. Chris and Karl unpack practical steps leaders can take to move from experimentation into operational transformation, including workflow discovery, data readiness, security, and ROI prioritization. Leaders looking to move beyond AI pilots and toward business redesign will find this episode especially valuable.

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