608. Why Imperfection Is Core to Being Human feat. Laurence D. Hurst

Episode notes

While evolution is often thought to be conducive to perfect adaptation, there are plenty of reasons why we never get there. Laurence D. Hurst is a professor of evolutionary genetics in the Milner Centre for Evolution at the University of Bath. His book, The Evolution of Imperfection: The Science of Why We Aren’t and Can’t Be Perfect is an expansive look into the imperfections of the human genome and why humans seem to be predisposed to so much bad genetic luck. Laurence and Greg explore the evolutionary constraints that lead to imperfections, how population size affects mutation rates, the advancements in gene therapy, and why imperfection could be key to a deeper understanding of evolution. *unSILOed Podcast is